1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).
2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.
3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.
Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:
Pharmacist signs for use duringolescence of tadalafil during the ejaculation of a patient during a patient consultation.
Patient signs of tadalafil duringolescence of tadalafil include sudden loss of vision, prolonged erections, and an erection that is painful or lasts longer than four hours. These signs may be permanent.
Tadalafil (and other phosphodiesterase (PDE) inhibitors) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects.
Cialis, also known by its generic name tadalafil, is a medication used primarily to treat erectile dysfunction (ED) and pulmonary arterial hypertension (PAH). This medication functions by relaxing the blood vessels in the penis, allowing increased blood flow during sexual stimulation. Cialis is a popular choice among men looking for effective alternatives to ED medications, as it is a well-known and trusted solution for those who have difficulty swallowing pills. The drug has been proven effective in numerous clinical trials, helping countless men to regain their sexual confidence and regain their health.
Cialis, also known as tadalafil, is a PDE5 inhibitor. It helps increase blood flow to the penis, facilitating erections. While it is not typically prescribed for erectile dysfunction (ED), Cialis can help men manage sexual health by increasing blood flow. It is typically taken orally, taken daily, and administered by mouth. It works by inhibiting PDE5, which allows more blood to flow into the penis, aiding in achieving and maintaining an erection. It is important to note that Cialis is not a cure for ED or PAH, but rather a means to manage symptoms of the condition. This medication is not intended for use by women or children, and it can affect fertility in men. The use of Cialis should be approached with caution, as it can have serious health risks, particularly in individuals with underlying health conditions or those taking medications. It is important to seek medical advice if you have underlying health conditions, or are taking other medications. Additionally, Cialis can interact with other medications, as it can cause side effects such as dizziness, headache, and nasal congestion. It is important to follow the prescribed dosage and instructions closely to ensure optimal effectiveness.
Cialis is typically taken orally, about 30 minutes to 1 hour before sexual activity. This medication works by increasing blood flow to the penis, aiding in achieving and maintaining an erection. It can also be taken with or without food, but the typical recommended dose is one tablet per day. It is generally recommended to start with a lower dose and gradually increase it as needed to maintain the desired effects. It is important to complete the full course of Cialis, even if you start feeling better, to ensure that the medication remains effective and safe for you. This medication is not intended for immediate relief from ED or PDE5 inhibitor-induced erectile dysfunction (ED), but it can be taken for up to 6 hours before sexual activity. It is essential to follow the recommended dosage and frequency of use to avoid potential side effects. It is important to note that Cialis is not intended for long-term use, and continuous use can lead to adverse effects. Regular monitoring and adjustments to your dosage are necessary, as it may not be suitable for everyone.
Cialis is generally well-tolerated, with most side effects typically mild and temporary. However, some individuals may experience side effects such as headache, facial flushing, nasal congestion, indigestion, and dizziness. It is essential to disclose any medical conditions or medications you are taking to avoid any potential risks. It is important to follow the prescribed dosage and timing of sexual activity, and never engage in foreplay or engage in other sexual activity without medical advice.
Cialis typically starts working within 30-60 minutes, and the recommended dose is one tablet taken before sexual activity. It is important to take the tablet with water, as this can help reduce stomach upset. The recommended dosage of Cialis is one tablet taken before sexual activity. It is important to take the tablet at least 30 minutes before sexual activity, and not more than one tablet within 24 hours. It is advisable to take Cialis at least 4 hours before sexual activity.
Before starting Cialis, it is important to consider several precautions and warnings. Firstly, it is important to inform your healthcare provider about any ongoing medical conditions you may have. This medication may not be suitable for individuals with cardiovascular, liver, or kidney disease. Additionally, it may interact with other medications, making it essential to disclose any current medications you are currently taking to avoid potential interactions. It is also important to note that Cialis is not intended for continuous daily use, and continuous use can lead to side effects such as dizziness, headache, and nasal congestion.
In a post posted at theInternational Journal of Clinical Pharmacology, Dr. Emily Carter of theUniversity of California, San Diego,said he has seen his patients with benign prostatic hyperplasia who are receiving the lowest Cialis dosage in the United States. The average dosage was 3.4 mg per day, he said. The most commonly prescribed dosage was 5 mg daily and a daily dose of 10 mg per day.
“I would think that is just fine,” Carter said. “I would say, ‘Yeah, I would take it for 5 days,’ but then after that, the dosage would start to change so the dosage would be a little lower than the usual.”
For the most part, Carter said, he has never had patients with benign prostatic hyperplasia prescribed Cialis, but he’s had to find out about the benefits and risks of taking it.
Dr. Carter is the president of the American Society for Sexual Medicine and is a professor of urology at the University of California, San Diego. He is also the chief of the Clinical Pharmacology Laboratory at the University of California, San Diego’s Department of Pharmacology.
Citing his experience with the drug, Dr. Carter said the American Society for Sexual Medicine recently recommended Cialis for patients who are experiencing sexual dysfunction and that the use of the drug is not a long-term solution.
“It’s very important to keep in mind that, in our practice, most men who are diagnosed with erectile dysfunction (ED) are relatively healthy,” Dr. Carter said. “But, at the same time, we do need to make sure the patients are not taking other medications.”
“The fact that it is not a long-term solution means that the patient is not getting enough relief,” said Dr. Susan McLeod, president of the American Society for Sexual Medicine.
“We want to make sure we are not compromising the patient,” McLeod said. “And that we have the resources to get patients to talk to their doctor about the side effects of any medication.”
For more on erectile dysfunction, see and.
A full list of clinical studies available at theUCLA Sexual Medicine Informationcan be found.VIDEORead more from the.
In addition to his clinical experience, Dr. Carter has published numerous articles on the use of Cialis in the treatment of erectile dysfunction. He has also been the author ofThe Medical Effectiveness and Erectile Dysfunction, which is available as a print book in a limited edition.
Carter is the director of the Sexual Medicine Program at the UCLA School of Medicine, and co-author of the bookWhat You Need to Know About Viagra and Cialis, published by Elsevier.
In an email, Dr. Carter said he has also published the bookand has also written an editorial in the, which is published by the American Society of Health-System Pharmacists.
and has written an editorial in the
This article was co-sponsored by.
Source:Reuters
A randomized, placebo-controlled trial was conducted to compare the efficacy and safety of sildenafil citrate (Viagra) with cialis, levitra, or sildenafil citrate and to evaluate the efficacy of the combination to control erectile dysfunction in patients who had been on ED treatment for at least six months.
A total of 79 patients with erectile dysfunction who were randomly assigned to sildenafil (n=42) or cialis (n=39) therapy and received an oral drug (n=21) and a drug combination of sildenafil or cialis (n=20) was compared at baseline to assess treatment efficacy and safety, and to assess treatment response (defined as achieving or maintaining at least a satisfactory response to oral sildenafil) and safety (defined as achieving or maintaining at least a satisfactory response to oral cialis, levitra or sildenafil). There was no difference in treatment success and safety between sildenafil and cialis, levitra, or sildenafil citrate (all P=0.622), but there was a statistically significant difference between the two treatment groups in terms of P for the presence of erectile dysfunction (P=0.003 for presence of erectile dysfunction vs. P for sildenafil, and P for presence of erectile dysfunction vs. levitra, respectively) and overall P for the presence of erectile dysfunction (P=0.006 for presence of erectile dysfunction vs. P for sildenafil, and P=0.003 for presence of erectile dysfunction vs. levitra, respectively).
There were no statistically significant differences in the efficacy or safety of sildenafil or cialis (all P=0.961), cialis (P=0.521), or levitra (P=0.934) at baseline between the two groups. There was a statistically significant difference in the incidence of clinically meaningful sexual dysfunction (P=0.008 for clinically meaningful sexual dysfunction vs. P for sildenafil, and P=0.003 for clinically meaningful sexual dysfunction vs. levitra, respectively) between sildenafil and cialis, levitra and sildenafil citrate, and sildenafil citrate and levitra versus cialis and sildenafil citrate. There were also no statistically significant differences in P for the presence of sexual dysfunction (P=0.531), clinically meaningful sexual dysfunction (P=0.814), or clinically meaningful sexual dysfunction (P=0.924) between sildenafil and cialis, levitra and sildenafil citrate, and levitra and sildenafil citrate vs. sildenafil citrate. Sildenafil was associated with clinically meaningful sexual dysfunction (P=0.003) and P for the presence of sexual dysfunction (P=0.003).
In conclusion, sildenafil citrate is well tolerated and effective in the treatment of erectile dysfunction in patients who have been on oral treatment for at least six months. The combination of sildenafil and cialis may be useful for patients with erectile dysfunction who have been taking other medications for ED or who are unable to tolerate oral medication.
The authors have no financial affiliations or issues with any materials, real or perceived, that have appeared in the supplement. The views expressed in the article are solely those of the authors and do not necessarily represent the views of the publisher.
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